What Drugs Are Used To Treat Histoplasmosis?

Where is histoplasmosis most common?

Histoplasma, the fungus that causes histoplasmosis, lives throughout the world, but it’s most common in North America and Central America..

How does a person get histoplasmosis?

People can get histoplasmosis after breathing in the microscopic fungal spores from the air. Although most people who breathe in the spores don’t get sick, those who do may have a fever, cough, and fatigue.

What does histoplasmosis look like on xray?

After heavy exposure, radiographs may show widely disseminated, diffuse, fairly discrete nodular shadows throughout the lungs, with individual lesions measuring 1-10 mm in diameter. This form of disease is termed miliary histoplasmosis (see the image below); it is similar to miliary tuberculosis.

Does histoplasmosis affect the liver?

Histoplasmosis is acquired by inhaling spores of the fungus. Most people do not have symptoms, but some feel sick and have a fever and cough, sometimes with difficulty breathing. Sometimes the infection spreads, causing the liver, spleen, and lymph nodes to enlarge and damaging other organs.

Can histoplasmosis affect the eyes?

Ocular histoplasmosis may affect both eyes, although the second eye may not become involved for many years. Ocular histoplasmosis is diagnosed with an eye examination involving dilation of the pupils.

What is the gold standard for treatment of histoplasmosis?

Isolation of H. capsulatum from clinical specimens remains the gold standard for the diagnosis of histoplasmosis.

What are the long term effects of histoplasmosis?

Some people with histoplasmosis also get joint pain and a rash. People who have a lung disease, such as emphysema, can develop a chronic form of histoplasmosis. Signs of chronic histoplasmosis can include weight loss and a bloody cough. The symptoms of chronic histoplasmosis sometimes mimic those of tuberculosis.

Can you have histoplasmosis for years?

Chronic. Chronic, or long-term, histoplasmosis occurs far less often than the acute form. In rare cases, it can spread throughout the body. Once histoplasmosis has spread throughout your body it is life-threatening if it isn’t treated.

Can histoplasmosis affect the brain?

These studies have demonstrated that the most common clinical features of CNS histoplasmosis consist of chronic meningitis, focal brain, or spinal cord lesions, stroke syndromes, encephalitis, and hydrocephalus.

What kind of doctor treats histoplasmosis?

You’re likely to start by seeing your primary care provider, who might refer you to a specialist in infectious diseases. Depending on your symptoms and the severity of your infection, you might also see other doctors, such as a lung specialist (pulmonologist) or a heart specialist (cardiologist).

How do you get rid of histoplasmosis?

Itraconazole is one type of antifungal medication that’s commonly used to treat histoplasmosis. Depending on the severity of the infection and the person’s immune status, the course of treatment can range from 3 months to 1 year.

Does chest xray show histoplasmosis?

A chest X-ray (CXR) may show that you have an infection, but histoplasmosis can look like many other conditions such as pneumonia, lung cancer or tuberculosis. A sample of your blood, sputum (phlegm) or other body fluids can be cultured to see if the fungus grows in the sample.

Does histoplasmosis ever go away?

For most people, the symptoms of histoplasmosis will go away within a few weeks to a month. However, some people have symptoms that last longer than this, especially if the infection becomes severe.

How long does it take to recover from histoplasmosis?

It can take between 2 weeks and several months for the infection to go away. When the condition leads to longer-term effects, it is said to be chronic.

What does histoplasmosis do to the body?

In most cases, histoplasmosis causes mild flu-like symptoms that appear between 3 and 17 days after exposure to the fungus. These symptoms include fever, chills, headache, muscle aches, cough and chest discomfort. In these milder forms, most symptoms go away on their own in a few weeks.